Non-degradative intracellular trafficking of highly compacted polymeric DNA nanoparticles
نویسندگان
چکیده
منابع مشابه
Efficient Non-Viral Ocular Gene Transfer with Compacted DNA Nanoparticles
BACKGROUND The eye is an excellent candidate for gene therapy as it is immune privileged and much of the disease-causing genetics are well understood. Towards this goal, we evaluated the efficiency of compacted DNA nanoparticles as a system for non-viral gene transfer to ocular tissues. The compacted DNA nanoparticles examined here have been shown to be safe and effective in a human clinical tr...
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ژورنال
عنوان ژورنال: Journal of Controlled Release
سال: 2012
ISSN: 0168-3659
DOI: 10.1016/j.jconrel.2011.10.031